Which medication is used as a treatment for an opioid overdose?

• A. Naloxone
• B. Epinephrine
• C. Glucose
• D. Atropine

Answer: (A)

Naloxone is the medication used to treat an opioid overdose. It works by binding to the same receptors in the brain (mu receptors) that opioids activate, effectively displacing the opioid molecules and reversing dangerous effects like slowed or stopped breathing and altered level of consciousness. It acts quickly, and can be given by injection or nasal spray depending on the setting. Because its effects may wear off before all opioids are cleared from the body, repeated dosing or observation in a medical setting is often necessary to prevent rebound overdose. After administration, ensure the airway is supported and monitor breathing and mental status. The other medications are used for different problems: epinephrine for severe allergic reactions or cardiac arrest, glucose for low blood sugar, and atropine for certain types of poisoning or bradycardia. They do not reverse opioid effects.